Completed Studies

Action 3:30 Action 3:30: A cluster randomised feasiblity trial evaluating teaching assistant led, extra curricular physical activity intervention for 8 to 10 year olds.
ADEPT ADEPT: Guided Self-Help for Depression in adults with Autism: A feasibility RCT
ARCADIA Association of non-coding RNAs with Coronary Artery Disease and type 2 Diabetes
AMIST A multicentre randomised controlled trial of minimally invasive direct coronary bypass grafting versus percutaneous transluminal coronary angioplasty with stenting for proximal stenosis of the left anterior descending coronary artery
BHACAS 1&2  Early and midterm outcome after off-pump and on-pump surgery in Beating Heart Against Cardioplegic Arrest Studies (BHACAS 1 and 2): a pooled analysis of two randomised controlled trials 
BLUEBELLE The Bluebelle study: a feasibility study of three wound dressing strategies in elective and unplanned surgery
CAIRO Improving Outcomes from Out of Hospital Cardiac Arrest: The Cardiac Arrest Individual Registry and Outcomes (CAIRO) Programme 
COPTIC Coagulation and platelet laboratory testing in cardiac surgery 
CRISP Coronary artery grafting in High Risk patients randomised to Off Pump or On Pump Surgery 
CORTISOL Ultradian rhythms of cortisol after cardiac surgery
CORTISOL 2 Cortisol profiles in the critically ill after cardiac surgery
ECHOES The Effectiveness of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease: a virtual trial 
ERICCA Effect of Remote Ischaemic preConditioning on clinical outcomes in patients undergoing Coronary Artery Bypass Graft surgery (ERICCA): A multicentre randomised controlled clinical trial 
EVARREST  A Single‐blinded, Randomized, Controlled, Comparative Phase III Study Evaluating the Safety and Effectiveness of EVARREST™ Fibrin Sealant Patch as an Adjunct to Hemostasis During Cardiovascular Surgery 
HARVEST  A randomised controlled trial to assess the extent of intimal Hyperplasia and Atherogenesis in bypass Vein grafts following different Surgical preparation Techniques
HepCATT  Evaluation of interventions designed to increase diagnosis and treatment of patients with Hepatitis C virus infection in primary care.  See outputs for this study.
INFORM A multi-centered randomised trial to compare 1 stage with 2 stage revision surgery for prosthetic hip joint infection
IVAN A randomised controlled trial of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN) 
IVAN Follow Up Five year observational follow-up of the IVAN trial cohort: a study of function and morphology
MONITOR Effectiveness and cost-effectiveness of serum B-type natriuretic peptide (BNP or NT-BNP) testing and monitoring in patients with heart failure (HF) in primary and secondary care 
NAPSACC A feasibility cluster randomised controlled trial in child care settings to increase physical activity and healthy eating in 2-4 year olds  
OXFORD ARTERY Role of potassium channels in sustaining physiological responses of human resistance arteries
OXIC2 A randomised controlled trial to compare normoxic versus standard cardiopulmonary bypass in cyanotic children undergoing cardiac surgery
PASPORT Patient-specific cerebral oxygenation monitoring as part of an algorithm to reduce transfusion during heart valve surgery: a randomised controlled trial
PINPOINT A study of platelet inhibition, using a ‘point of care’ platelet function test, following primary percutaneous coronary intervention for ST elevation myocardial infarction 
PIPA Benefit to patients and the NHS of cardiac magnetic resonance imaging (CMR) after Primary percutaneous coronary Intervention (PPCI) Pathway Activation
PROMPT Propofol cardioplegia for Myocardial Protection Trial 
RADAR Reducing Alzheimer’s Disease through Angiotensin TaRgetting
 RAFT Reducing Arthritis Fatigue – clinical Teams using cognitive-behavioural approaches  
REST The Runny Ear Study (REST) will focus on children who have middle ear infections with discharge (AOMd)
 ROLO  The Renoprotective value of Leukodepletion in Heart Valve surgery: an external feasibility randomised controlled trial
 SKARF Determination of the SK channel composition contributing to atrial action potential duration and of predictors of response to treatments in patients with or without atrial fibrillation
STET A randomised controlled trial of median sternotomy vs. anterolateral left thoracotomy on morbidity and healthcare resource use in patients having off-pump coronary artery bypass surgery 
TARGET Randomised controlled trial to compare the diagnostic yield of Positron Emission Tomography Computed Tomography (PET-CT) TARGETed pleural biopsy versus CT-guided pleural biopsy in suspected pleural malignancy
TEMPLATE A Randomised Controlled Trial Investigating the Pharmacodynamic Effect of Ticagrelor Monotherapy on Platelet Reactivity in Patients with Coronary Artery Disease: The TEMPLATE Study
TEST TEST (Trial of Eczema allergy Screening Tests) is a feasibility study to help determine if routine allergy tests can help treatment of children with eczema.
THERMIC2 A Randomised Controlled Trial to Compare Normothermic Versus Hypothermic Cardiopulmonary Bypass in Children Undergoing Open Heart Surgery 
Travel to Work The effectiveness and cost effectiveness of an employer-led intervention to increase walking during the daily commute: Cluster randomised controlled trial.  See outputs to this study.
TITRE2 A multi-centre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and healthcare resource use following cardiac surgery 
VERDICT Preoperative Volume Replacement vs. usual care in Diabetic patients having CABG surgery: a randomised controlled trial
VICI Clinical efficacy and mechanistic evaluation of Eplerenone for central serous chorio-retinopathy – the VICI randomised trial 
VICTORY Prospective, randomised, controlled investigation comparing the safety and performance of 032-11 surgical haemostat 2g applicator with FLOSEAL hemostatic matrix as an adjunctive haemostat in cardiac surgery and thoracic surgery 
UNBLOCS   A randomised controlled trial to determine the clinical and cost effectiveness of thulium laser transurethral vaporesection of the prostate (ThuVARP) versus transurethral resection of the prostate (TURP) in the National Health Service (NHS) 
WISE WISE: A cluster randomised controlled trial evaluating an intervention to improve the mental health support and training available to secondary school teachers